MeriTalk: NIH Seeks Help Analyzing Alzheimer’s Research Data in Cloud-Based Platforms

“The National Institute of Health (NIH) is looking for help processing large amounts of data stemming from its research into Alzheimer’s disease and other dementia conditions.”

“In a post on Beta.Sam.gov, NIH said its Center for Alzheimer’s and Related Dementias (CARD) will generate long-read sequencing data from roughly 4000 patients with Alzheimer’s disease, frontotemporal dementia, Lewy body dementia, and healthy subjects.”

“This project will produce roughly 8000 terabytes of data. NIH said CARD will need a contractor to help it develop pipelines for storing, analyzing, and harmonizing these data sets on cloud-based computing platforms.”

“The RFI also said that after creating data pipelines, the contractor will use datasets to identify DNA “methylation changes and single nucleotide variants,” which CARD says are important to research further as they have been linked to normal aging and neurodegenerative diseases.”

“’The government will then use this service provided by the contractor to evaluate how the epigenetic and genomic landscape in challenging regions contribute to the development of neurodegenerative diseases,’ the RFI says…” Read the full article here.

Source: NIH Seeks Help Analyzing Alzheimer’s Research Data in Cloud-Based Platforms — By Kate Polit, April 7, 2021. MeriTalk.

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